Phosphate starvation promotes swarming motility and cytotoxicity of Pseudomonas aeruginosa.

نویسندگان

  • Manjeet Bains
  • Lucía Fernández
  • Robert E W Hancock
چکیده

We investigated the transcriptional responses of Pseudomonas aeruginosa under phosphate-deficient (0.2 mM) conditions compared to phosphate sufficiency (1 mM). This elicited enormous transcriptional changes in genes related to phosphate acquisition, quorum sensing, chemotaxis, toxin secretion, and regulation. This dysregulation also led to increased virulence-associated phenotypes, including swarming motility and cytotoxicity.

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عنوان ژورنال:
  • Applied and environmental microbiology

دوره 78 18  شماره 

صفحات  -

تاریخ انتشار 2012